INT246068

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Context Info
Confidence 0.24
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GCLC) small molecule metabolic process (GCLC) cellular nitrogen compound metabolic process (GCLC)
ligase activity (GCLC) cytoplasm (GCLC)
GCLC (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 2 61.76 Quite High
Toxicity 15 51.16 Quite High
Death 18 5.00 Very Low Very Low Very Low
Apoptosis 17 5.00 Very Low Very Low Very Low
Cancer 8 5.00 Very Low Very Low Very Low
Breast Cancer 3 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Lung Cancer 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One of the major functions of Nrf2 is to regulate an antioxidant response by up-regulating intracellular antioxidants and genes such as GCS and the xCT cysteine antiporter that encode key enzymes in the synthesis of glutathione.
Regulation (regulating) of GCS
1) Confidence 0.24 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2535615 Disease Relevance 0.11 Pain Relevance 0

General Comments

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