INT246120

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Context Info
Confidence 0.62
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 9
Disease Relevance 8.84
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Capn10) intracellular (Capn10) cytoplasm (Capn10)
cytosol (Capn10) cytoskeletal protein binding (Capn10) peptidase activity (Capn10)
Anatomy Link Frequency
skeletal muscle 2
liver 1
pancreas 1
body 1
Capn10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 9 66.96 Quite High
anesthesia 9 5.00 Very Low Very Low Very Low
imagery 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 207 99.88 Very High Very High Very High
Diabetic Angiopathy 18 99.80 Very High Very High Very High
Obesity 288 97.60 Very High Very High Very High
Insulin Resistance 45 97.52 Very High Very High Very High
Diabetes Mellitus 360 93.40 High High
Adhesions 18 93.00 High High
Vasculitis 9 66.96 Quite High
Stomach Cancer 9 66.04 Quite High
Frailty 9 65.04 Quite High
Cataract 9 63.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings suggested the related genetic and product expression of calpain-10 might play a major role in determining the normal response of skeletal muscle to the effects of insulin.
Gene_expression (expression) of calpain-10 in skeletal muscle
1) Confidence 0.62 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.87 Pain Relevance 0
Calpain-10 is a non-lysosomal cysteine protease expressed in many tissues, including skeletal muscle, liver, and pancreas 13.
Gene_expression (expressed) of Calpain-10 in liver
2) Confidence 0.54 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.97 Pain Relevance 0.03
We also observed the expressions of calpain 10, ?
Gene_expression (expressions) of calpain 10
3) Confidence 0.54 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 1.18 Pain Relevance 0
Furthermore, the calpain 10 expression of LS groups was lower than that pf LE groups.
Gene_expression (expression) of calpain 10
4) Confidence 0.54 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.74 Pain Relevance 0
After 2-month exercise (treadmill running), the body weight (BW) and expression of calpain 10, ?
Gene_expression (expression) of calpain 10 in body associated with body weight
5) Confidence 0.54 Published 2008 Journal International Journal of Biological Sciences Section Abstract Doc Link PMC2536707 Disease Relevance 1.16 Pain Relevance 0
In contrast, there was no significant difference in calpain 10 expression between OE and OS groups.
Gene_expression (expression) of calpain 10
6) Confidence 0.47 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.69 Pain Relevance 0
The calpain 10 expression of LS rats (0.965) was lower than that of LE rats (1.006), whereas those of OS and OE were comparable.
Gene_expression (expression) of calpain 10
7) Confidence 0.47 Published 2008 Journal International Journal of Biological Sciences Section Abstract Doc Link PMC2536707 Disease Relevance 1.28 Pain Relevance 0
Calpain-10 is a non-lysosomal cysteine protease expressed in many tissues, including skeletal muscle, liver, and pancreas 13.
Gene_expression (expressed) of Calpain-10 in skeletal muscle
8) Confidence 0.18 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.97 Pain Relevance 0.03
Calpain-10 is a non-lysosomal cysteine protease expressed in many tissues, including skeletal muscle, liver, and pancreas 13.
Gene_expression (expressed) of Calpain-10 in pancreas
9) Confidence 0.18 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.97 Pain Relevance 0.03

General Comments

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