INT246123

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Context Info
Confidence 0.50
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 3.89
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Capn10) intracellular (Capn10) cytoplasm (Capn10)
cytosol (Capn10) cytoskeletal protein binding (Capn10) peptidase activity (Capn10)
Capn10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
imagery 5 49.36 Quite Low
Inflammation 5 46.40 Quite Low
anesthesia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 200 98.90 Very High Very High Very High
Insulin Resistance 25 97.40 Very High Very High Very High
Obesity 160 90.48 High High
Body Weight 115 84.88 Quite High
Diabetic Angiopathy 10 79.24 Quite High
Adhesions 10 72.44 Quite High
Vasculitis 5 46.40 Quite Low
Autolysis 15 39.88 Quite Low
Cataract 5 5.00 Very Low Very Low Very Low
Hypertrophy 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NIDDM-associated SNP-43*G-allele is associated with reduced calpain 10 mRNA levels, when compared to SNP-43*A-allele 36.
Transcription (levels) of calpain 10 associated with diabetes mellitus
1) Confidence 0.50 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.76 Pain Relevance 0
In contrast, in the lean group, the calpain 10 mRNA expression of sedentary rats (LS) was significantly lower than in exercise rats (LE) (0.965 ± 0.031 vs. 1.006 ± 0.024; p < 0.05; Figure 2B).
Transcription (expression) of calpain 10
2) Confidence 0.50 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.90 Pain Relevance 0
Insulin had no significant effect upon calpain 10 mRNA levels 36.
Transcription (levels) of calpain 10
3) Confidence 0.50 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.75 Pain Relevance 0
We also observed the lean Zucker rats with a Fa/Fa or Fa/fa genotype have decreased levels of calpain 10 mRNA.
Transcription (levels) of calpain 10
4) Confidence 0.48 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.74 Pain Relevance 0
In addition, age had no significant influence on calpain 10 mRNA levels 36.
Transcription (levels) of calpain 10
5) Confidence 0.37 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2536707 Disease Relevance 0.74 Pain Relevance 0

General Comments

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