INT246170

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Context Info
Confidence 0.34
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (EEF2) translation (EEF2) GTPase activity (EEF2)
cytoplasm (EEF2)
Anatomy Link Frequency
leg 2
EEF2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperinsulinism 6 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low
Muscular Atrophy 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specifically, the insulin dose-related increases in the phosphorylation of PKB and p70S6k and dose-dependent decreases in the phosphorylation of eEF2 are not reflected in any way by dose-related changes in MPS or leg turnover.
Negative_regulation (decreases) of Phosphorylation (phosphorylation) of eEF2 in leg
1) Confidence 0.34 Published 2008 Journal American Journal of Physiology - Endocrinology and Metabolism Section Body Doc Link PMC2536736 Disease Relevance 0 Pain Relevance 0
Increasing serum insulin concentration during the mixed amino acid infusion produced insulin dose-related increases in the phosphorylation status of PKB Ser473 and p70S6k Thr389 and dose-related decreases in eEF2 Thr56 phosphorylation status relative to the values at 5 mU/l (Fig. 5A).
Negative_regulation (decreases) of Phosphorylation (phosphorylation) of eEF2
2) Confidence 0.25 Published 2008 Journal American Journal of Physiology - Endocrinology and Metabolism Section Body Doc Link PMC2536736 Disease Relevance 0 Pain Relevance 0

General Comments

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