INT246194

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Context Info
Confidence 0.34
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.31
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MTOR) Golgi apparatus (MTOR) endoplasmic reticulum (MTOR)
cytoplasm (MTOR) cytosol (MTOR) signal transduction (MTOR)
MTOR (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 6 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Muscular Atrophy 101 97.16 Very High Very High Very High
Frailty 28 70.76 Quite High
Hypertrophy 2 70.28 Quite High
Stress 8 5.00 Very Low Very Low Very Low
Parkinson's Disease 6 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Hyperinsulinism 3 5.00 Very Low Very Low Very Low
Obesity 3 5.00 Very Low Very Low Very Low
Nicotine Addiction 2 5.00 Very Low Very Low Very Low
Hypokinesia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results highlight the importance of mitochondrial down-regulation, decreased mTOR phosphorylation, and increased protein ubiquitination during the early phases of the muscular response to immobilization in humans.
Regulation (regulation) of Phosphorylation (phosphorylation) of mTOR
1) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2716517 Disease Relevance 0.10 Pain Relevance 0
Another study, however, failed to detect any significant changes in the phosphorylation of Akt, mTOR, p70S6K, eEF2, eIF4E, and TSC2 in men following 10 and 21 d of ULS [26].
Regulation (changes) of Phosphorylation (phosphorylation) of mTOR
2) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2716517 Disease Relevance 0.21 Pain Relevance 0
Although this pattern was not seen for the changes in phosphorylation of mTOR, 4E-BP1, and GSK-3?
Regulation (changes) of Phosphorylation (phosphorylation) of mTOR
3) Confidence 0.21 Published 2008 Journal American Journal of Physiology - Endocrinology and Metabolism Section Body Doc Link PMC2536736 Disease Relevance 0 Pain Relevance 0

General Comments

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