INT246309

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.09
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrnb1) transport (Chrnb1) plasma membrane (Chrnb1)
neurological system process (Chrnb1)
Anatomy Link Frequency
muscle 1
Chrnb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Action potential 25 87.20 High High
medulla 30 79.68 Quite High
Neurotransmitter 8 50.80 Quite High
gABA 18 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
tetrodotoxin 5 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 10 92.48 High High
Death 10 27.36 Quite Low
Cyanosis 2 19.72 Low Low
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 5 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Fasciculation 4 5.00 Very Low Very Low Very Low
Poisoning 3 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By 24 days, the AChR clusters are much brighter and are more clearly defined.
Negative_regulation (defined) of AChR
1) Confidence 0.09 Published 2008 Journal The Journal of Physiology Section Body Doc Link PMC2538785 Disease Relevance 0 Pain Relevance 0.03
Taken together, apart from the loss of AChR clusters, the development of NMJs of TGF-?
Negative_regulation (loss) of AChR
2) Confidence 0.06 Published 2008 Journal Neural Develop Section Body Doc Link PMC2576228 Disease Relevance 0 Pain Relevance 0
The reduction of AChR clusters could therefore be a muscle-intrinsic problem, as it is known that TGF-?
Negative_regulation (reduction) of AChR in muscle
3) Confidence 0.05 Published 2008 Journal Neural Develop Section Body Doc Link PMC2576228 Disease Relevance 0.09 Pain Relevance 0.11

General Comments

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