INT246581

Context Info Confidence 0.11 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.22 Pain Relevance 0.04

signal transduction (VLDLR) transport (VLDLR) extracellular space (VLDLR) plasma membrane (VLDLR) nucleus (VLDLR)

Anatomy Link Frequency liver 2 VLDLR (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 4 77.52 Angina 4 5.00 ischemia 4 5.00 withdrawal 1 5.00 rheumatoid arthritis 1 5.00 Arthritis 1 5.00 alcohol 1 5.00 Bioavailability 1 5.00

Disease Link Frequency Relevance Heat Increased Venous Pressure Under Development 11 83.84 INFLAMMATION 4 77.52 Coronary Artery Disease 49 60.88 Myocardial Infarction 24 40.96 Stroke 18 5.00 Disorder Of Lipid Metabolism 9 5.00 Death 8 5.00 Atherosclerosis 7 5.00 Rhabdomyolysis 7 5.00 Cancer 6 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Reductions in the hepatic pool of cholesterol have been associated with a decrease in the rate of production of very-low-density lipoprotein (VLDL) by the liver (Thompson et al 1996).

Negative_regulation (decrease) of Gene_expression (production) of very-low-density lipoprotein in liver

1) Confidence 0.11 Published 2008 Journal Clinical Interventions in Aging Section Body Doc Link PMC2546474 Disease Relevance 0.22 Pain Relevance 0.04

General Comments

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