INT24662

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Context Info
Confidence 0.55
First Reported 1989
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 3.01
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (F2RL3) extracellular region (F2RL3) plasma membrane (F2RL3)
signal transducer activity (F2RL3)
Anatomy Link Frequency
plasma 2
neutrophil 1
F2RL3 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 1 96.96 Very High Very High Very High
Inflammation 12 95.04 Very High Very High Very High
cytokine 6 88.80 High High
Calcium channel 2 87.36 High High
Dismenorea 2 83.24 Quite High
abdominal pain 4 79.44 Quite High
headache 1 76.20 Quite High
cOX1 2 70.96 Quite High
Crohn's disease 14 50.00 Quite Low
cva 3 50.00 Quite Low
Disease Link Frequency Relevance Heat
Systemic Lupus Erythematosus 1 99.92 Very High Very High Very High
Metastasis 2 99.82 Very High Very High Very High
Prostate Cancer 5 99.32 Very High Very High Very High
Thrombophilia 1 99.02 Very High Very High Very High
Benign Prostatic Hypertrophy 2 95.66 Very High Very High Very High
INFLAMMATION 11 95.04 Very High Very High Very High
Dysmenorrhea 2 83.24 Quite High
Anaphylaxis 1 82.12 Quite High
Cancer 4 81.12 Quite High
Bacteremia 2 81.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We reported the up-regulation in gene expression of two of its cellular receptors, F2R and F2RL3 at labour [12].
Gene_expression (expression) of F2RL3
1) Confidence 0.55 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2645409 Disease Relevance 0.22 Pain Relevance 0.15
We have reported an increase in mRNA and protein expression of F2R and F2RL3 at labour [12].
Gene_expression (expression) of F2RL3
2) Confidence 0.55 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2645409 Disease Relevance 0.42 Pain Relevance 0.25
Thrombophilia studies were normal and included fasting plasma levels of protein C, protein S, anti-thrombin III, lupus anticoagulant, anti-cardiolipin and anti-phospholipid antibodies, antinuclear antibodies, and genetic testing for the factor V Leiden.
Gene_expression (levels) of anti-thrombin III in plasma associated with thrombophilia and systemic lupus erythematosus
3) Confidence 0.06 Published 2007 Journal BMC Gastroenterol Section Body Doc Link PMC1904453 Disease Relevance 0.94 Pain Relevance 0.14
Human neutrophil elastase complexed to alpha 1-antitrypsin was increased in the patient's plasma, while the levels of the complexes thrombin-antithrombinIII and plasmin-alpha 2-antiplasmin, indicating recent coagulation or fibrinolysis, respectively, were not elevated.
Gene_expression (levels) of thrombin-antithrombinIII in neutrophil
4) Confidence 0.04 Published 1989 Journal Toxicology Section Abstract Doc Link 2469140 Disease Relevance 0.70 Pain Relevance 0.08
In 49 patients with benign prostatic hyperplasia, 24 metastatic prostatic carcinoma patients all under palliative hormonal treatment, 17 untreated prostatic carcinoma patients without metastases and 14 untreated prostatic carcinoma patients with metastases, plasma levels of thrombin-antithrombin III complex, D-dimer and plasmin-alpha2-antiplasmin were determined.
Gene_expression (levels) of thrombin-antithrombin III in plasma associated with benign prostatic hypertrophy, prostate cancer, metastasis and palliative
5) Confidence 0.01 Published 1997 Journal Eur J Clin Chem Clin Biochem Section Abstract Doc Link 9056745 Disease Relevance 0.74 Pain Relevance 0.10

General Comments

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