INT246835

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Iars, Ins1) extracellular space (Ins1) extracellular region (Ins1)
nucleus (Iars) carbohydrate metabolic process (Ins1) translation (Iars)
Anatomy Link Frequency
skeletal muscle 1
Iars (Mus musculus)
Ins1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 7 54.80 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 24 100.00 Very High Very High Very High
Diabetes Mellitus 7 92.80 High High
Targeted Disruption 8 75.00 Quite High
Impaired Glucose Tolerance 9 55.44 Quite High
Hyperinsulinism 2 53.28 Quite High
Obesity 8 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we examine the role of serine phosphorylation of insulin receptor substrate (IRS)-1 in mediating fat-induced insulin resistance in skeletal muscle in vivo.
IRS Spec (examine) Positive_regulation (induced) of insulin in skeletal muscle associated with insulin resistance
1) Confidence 0.06 Published 2008 Journal Diabetes Section Abstract Doc Link PMC2551673 Disease Relevance 0.86 Pain Relevance 0.03

General Comments

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