INT246854

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (SPAG8) biological_process (SPAG8)
SPAG8 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 41 100.00 Very High Very High Very High
corticosteroid 3 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Impaired Glucose Tolerance 43 100.00 Very High Very High Very High
Weight Loss 3 98.48 Very High Very High Very High
Obesity 35 73.20 Quite High
Insulin Resistance 25 60.72 Quite High
Diabetes Mellitus 15 58.80 Quite High
Abdominal Obesity 1 56.60 Quite High
Syndrome 1 53.68 Quite High
Hyperglycemia 1 23.32 Low Low
Polycystic Ovary Syndrome 5 5.00 Very Low Very Low Very Low
Reprotox - General 1 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-HSD1 inhibitors administered to rodents and primates decrease local glucocorticoid generation, improve glucose tolerance, increase insulin sensitivity, and may promote weight loss (14–17).
Positive_regulation (increase) of Negative_regulation (inhibitors) of HSD1 associated with weight loss, tolerance and impaired glucose tolerance
1) Confidence 0.49 Published 2008 Journal Diabetes Section Body Doc Link PMC2551674 Disease Relevance 0.86 Pain Relevance 0.05

General Comments

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