INT247022

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Context Info
Confidence 0.46
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.47
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Agtr1a) aging (Agtr1a) Golgi apparatus (Agtr1a)
plasma membrane (Agtr1a) cytoplasm (Agtr1a) signal transducer activity (Agtr1a)
Anatomy Link Frequency
brainstem 1
Agtr1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 7 99.84 Very High Very High Very High
cva 5 97.60 Very High Very High Very High
ischemia 15 78.08 Quite High
Glutamate 9 56.36 Quite High
antagonist 3 31.44 Quite Low
gABA 14 6.24 Low Low
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Renal Failure 37 99.12 Very High Very High Very High
Stress 11 98.52 Very High Very High Very High
Cv General 3 Under Development 3 97.60 Very High Very High Very High
Hypertension 6 88.64 High High
Pressure And Volume Under Development 19 84.88 Quite High
Middle Cerebral Artery Infarction 27 83.56 Quite High
Cv Unclassified Under Development 6 78.08 Quite High
Brain Hemorrhage 5 50.00 Quite Low
Cv General 4 Under Development 10 45.04 Quite Low
Overdose 1 40.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The AT1 mRNA expression in brainstem tissue was significantly decreased in CRF rats compared to C group (AT1-CRF, 0.16 ± 0.03 and C, 0.66 ± 0.09?
Transcription (expression) of AT1 in brainstem associated with medulla and chronic renal failure
1) Confidence 0.46 Published 2010 Journal International Journal of Hypertension Section Body Doc Link PMC3022169 Disease Relevance 1.15 Pain Relevance 0.13
We have observed that acute cerebral infarction followed by reperfusion in the rat is accompanied by upregulation of the functional contractile phenotype and the mRNA expression of endothelin ETB and angiotensin AT1 receptors [6,7].
Transcription (expression) of AT1 associated with cva
2) Confidence 0.21 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2553085 Disease Relevance 0.32 Pain Relevance 0.09

General Comments

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