INT247101

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.78
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL10RA) plasma membrane (IL10RA) signal transducer activity (IL10RA)
IL10RA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 44 87.52 High High
Inflammatory response 12 86.48 High High
COX2 3 64.68 Quite High
cytokine 27 35.36 Quite Low
cva 18 5.00 Very Low Very Low Very Low
Dismenorea 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Esophageal Disease 36 89.28 High High
INFLAMMATION 56 87.52 High High
Pneumonia 36 78.00 Quite High
Nicotine Addiction 32 65.92 Quite High
Toxicity 20 50.00 Quite Low
Premature Birth 15 50.00 Quite Low
Stomach Cancer 1 49.88 Quite Low
Birth Weight 3 12.76 Low Low
Non-small-cell Lung Cancer 8 9.88 Low Low
Hemorrhage 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL10:rs1800872 and IL10RA:rs3135932 have been shown to decrease IL10 signaling by decreasing serum levels and altering IL10-IL10RA interactions, respectively [26], [27].
IL10RA Binding (interactions) of
1) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2928273 Disease Relevance 0.72 Pain Relevance 0.19
In the fetal data the most significant ORs were for IL-10RA rs17121510, KL rs522796 (OR?
IL-10RA rs17121510 Binding (were) of
2) Confidence 0.15 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2553267 Disease Relevance 0.07 Pain Relevance 0
Five genes from maternal data (CRHBP, FV, IL-5, tPA, and PTGER3) and three in fetal data (CBS, IL-10RA, and TREM1) that showed highly significant associations with PTB were analyzed for haplotype association.
IL-10RA Spec (analyzed) Binding (association) of
3) Confidence 0.15 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2553267 Disease Relevance 0 Pain Relevance 0
Five genes from maternal data (CRHBP, FV, IL-5, tPA, and PTGER3) and three in fetal data (CBS, IL-10RA, and TREM1) that showed highly significant associations with PTB were analyzed for haplotype association.
IL-10RA Binding (associations) of
4) Confidence 0.15 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2553267 Disease Relevance 0 Pain Relevance 0

General Comments

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