INT247281

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.98
Pain Relevance 1.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HRAS) signal transduction (HRAS) Golgi apparatus (HRAS)
plasma membrane (HRAS) nucleus (HRAS) GTPase activity (HRAS)
Anatomy Link Frequency
joints 2
GLC1N (Homo sapiens)
HRAS (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 28 99.52 Very High Very High Very High
Pain 16 98.00 Very High Very High Very High
Analgesic 2 59.60 Quite High
Inflammation 6 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 36 99.52 Very High Very High Very High
Pain 16 98.00 Very High Very High Very High
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since GlcN is an important building block of HA and HA is found in high amounts in articular joints, increasing HA production through the administration of GlcN might be a way to explain the pain relieving effect of GlcN.
GlcN Negative_regulation (block) of HA in joints associated with pain
1) Confidence 0.02 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2553787 Disease Relevance 0.99 Pain Relevance 0.81
Since GlcN is an important building block of HA and HA is found in high amounts in articular joints, increasing HA production through the administration of GlcN might be a way to explain the pain relieving effect of GlcN.
GlcN Negative_regulation (block) of HA in joints associated with pain
2) Confidence 0.01 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2553787 Disease Relevance 0.99 Pain Relevance 0.81

General Comments

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