INT24742

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Context Info
Confidence 0.37
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 0.18
Pain Relevance 4.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Calca, Vip) extracellular space (Calca) aging (Calca)
nucleus (Calca) intracellular (Calca) cytoplasm (Calca)
Anatomy Link Frequency
nerves 4
Calca (Rattus norvegicus)
Vip (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 36 100.00 Very High Very High Very High
substance P 32 100.00 Very High Very High Very High
Dorsal horn 4 92.64 High High
Neuropeptide 16 82.48 Quite High
Spinal cord 4 81.76 Quite High
c fibre 12 75.00 Quite High
intrathecal 4 75.00 Quite High
Sciatic nerve 4 67.72 Quite High
Disease Link Frequency Relevance Heat
Shock 4 63.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In animals with sectioned nerves, SP and CGRP did not interact, whereas VIP and CGRP had a stronger facilitatory interaction.
CGRP Binding (interaction) of VIP in nerves associated with calcitonin gene-related peptide and substance p
1) Confidence 0.37 Published 1989 Journal Brain Res. Section Abstract Doc Link 2472853 Disease Relevance 0 Pain Relevance 1.10
In animals with intact nerves, SP and CGRP had a strong synergistic effect, whereas VIP and CGRP had a weak facilitatory interaction.
CGRP Binding (interaction) of VIP in nerves associated with calcitonin gene-related peptide and substance p
2) Confidence 0.37 Published 1989 Journal Brain Res. Section Abstract Doc Link 2472853 Disease Relevance 0.05 Pain Relevance 1.18
Since SP and VIP both coexist with CGRP in separate populations of primary afferents, the interaction between SP plus CGRP and VIP plus CGRP was tested in animals with intact and sectioned nerves.
CGRP Binding (interaction) of VIP in nerves associated with calcitonin gene-related peptide and substance p
3) Confidence 0.37 Published 1989 Journal Brain Res. Section Abstract Doc Link 2472853 Disease Relevance 0.06 Pain Relevance 1.21
Since SP and VIP both coexist with CGRP in separate populations of primary afferents, the interaction between SP plus CGRP and VIP plus CGRP was tested in animals with intact and sectioned nerves.
CGRP Binding (interaction) of VIP in nerves associated with calcitonin gene-related peptide and substance p
4) Confidence 0.37 Published 1989 Journal Brain Res. Section Abstract Doc Link 2472853 Disease Relevance 0.06 Pain Relevance 1.19

General Comments

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