INT247435

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.20
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SNRNP70) transport (APOB) small molecule metabolic process (APOB)
endoplasmic reticulum (APOB) enzyme binding (APOB) lipid metabolic process (APOB)
Anatomy Link Frequency
Hip 2
APOB (Homo sapiens)
SNRNP70 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 132 100.00 Very High Very High Very High
Hypertension 81 100.00 Very High Very High Very High
Coronary Artery Disease 168 99.56 Very High Very High Very High
Reprotox - General 1 3 93.20 High High
Diabetes Mellitus 42 68.16 Quite High
Schizophrenia 3 20.00 Low Low
Obesity 30 9.16 Low Low
Familial Combined Hyperlipidemia 18 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 18 5.00 Very Low Very Low Very Low
Nicotine Addiction 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, the Sac1 and the -75G>A SNPs showed significantly high LOD scores, implying linkage of these two loci to CAD as well as tentative linkage of the Sac1 SNP to TC, HDL-cholesterol and ApoB by QTL analysis.
ApoB Binding (linkage) of SNP associated with coronary artery disease and disorder of lipid metabolism
1) Confidence 0.04 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2556320 Disease Relevance 0.98 Pain Relevance 0
The standardized regression co-efficient data indicated that component 1 and component 2, characterized by the Sac-1 SNP, the -75 G>A SNP and HTN, were significantly associated with TG (0.154, p < 0.008) for the first component, TG (B = -0.147, p < 0.011) and ApoB (B = – 0.194, p < 0.001) for the second component while the component 3, characterized by DM, was associated with the Waist Hip Ratio (B = 0.117, p = 0.049) (Table 7).
ApoB Binding (associated) of SNP in Hip associated with hypertension
2) Confidence 0.04 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2556320 Disease Relevance 0.61 Pain Relevance 0
The standardized regression co-efficient data indicated that component 1 and component 2, characterized by the Sac-1 SNP, the -75 G>A SNP and HTN, were significantly associated with TG (0.154, p < 0.008) for the first component, TG (B = -0.147, p < 0.011) and ApoB (B = – 0.194, p < 0.001) for the second component while the component 3, characterized by DM, was associated with the Waist Hip Ratio (B = 0.117, p = 0.049) (Table 7).
ApoB Binding (associated) of SNP in Hip associated with hypertension
3) Confidence 0.04 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2556320 Disease Relevance 0.61 Pain Relevance 0

General Comments

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