INT247440

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Context Info
Confidence 0.28
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (APOA1, APOB) enzyme binding (APOA1, APOB) lipid metabolic process (APOA1, APOB)
extracellular space (APOA1, APOB) extracellular region (APOA1, APOB) plasma membrane (APOA1, APOB)
APOA1 (Homo sapiens)
APOB (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 56 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 44 100.00 Very High Very High Very High
Hypertension 27 100.00 Very High Very High Very High
Reprotox - General 1 1 67.28 Quite High
Diabetes Mellitus 14 5.00 Very Low Very Low Very Low
Obesity 10 5.00 Very Low Very Low Very Low
Familial Combined Hyperlipidemia 6 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 6 5.00 Very Low Very Low Very Low
Nicotine Addiction 6 5.00 Very Low Very Low Very Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study consisting of a cohort of affected sibling pairs selected from Asian Indian families with a strong history of premature CAD, the APOC3, Sac-1 and the ApoA1, -75G>A SNPs along with hypertension were the significant contributory factors to the CAD trait, probably mediated through their association with lipid and lipoprotein traits, particularly TC, TG and Apo B.
ApoA1 Binding (association) of Apo B associated with coronary artery disease, hypertension and disorder of lipid metabolism
1) Confidence 0.28 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2556320 Disease Relevance 1.02 Pain Relevance 0

General Comments

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