INT247475

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.45
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ITPR3) small molecule metabolic process (ITPR3) endoplasmic reticulum (ITPR3)
transmembrane transport (ITPR3) cytoplasm (ITPR3) signal transducer activity (P2RY6)
Anatomy Link Frequency
nasal 2
P2RY6 (Homo sapiens)
ITPR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 4 90.68 High High
Multiple sclerosis 2 82.56 Quite High
cytokine 14 61.52 Quite High
Sumatriptan 2 41.20 Quite Low
Migraine 2 28.32 Quite Low
Pyramidal cell 2 21.76 Low Low
Hippocampus 4 21.12 Low Low
gABA 8 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 2 82.56 Quite High
Apoptosis 6 75.96 Quite High
Nervous System Malformation 2 65.96 Quite High
Epstein-barr Virus 2 40.64 Quite Low
Bordatella Infection 6 32.76 Quite Low
Headache 2 28.32 Quite Low
Wound Healing 4 13.60 Low Low
Disorder Of Lipid Metabolism 6 5.00 Very Low Very Low Very Low
Loss Of Sense Of Smell 4 5.00 Very Low Very Low Very Low
Male Infertility 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pyrimidinergic receptor P2Y6 (p2ry6) is expressed in human nasal epithelial cells and activates the IP3 signaling pathway in the presence of UDP, and regulates mucin and fluid secretion [49].
Pyrimidinergic receptor P2Y6 Positive_regulation (activates) of IP3 in nasal
1) Confidence 0.01 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2556351 Disease Relevance 0.22 Pain Relevance 0.12
Pyrimidinergic receptor P2Y6 (p2ry6) is expressed in human nasal epithelial cells and activates the IP3 signaling pathway in the presence of UDP, and regulates mucin and fluid secretion [49].
p2ry6 Positive_regulation (activates) of IP3 in nasal
2) Confidence 0.01 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2556351 Disease Relevance 0.22 Pain Relevance 0.12

General Comments

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