INT247559

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.64
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hif1a) signal transduction (Hif1a) nucleolus (Hif1a)
nucleus (Hif1a) protein binding transcription factor activity (Hif1a) DNA binding (Hif1a)
Hif1a (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 5 90.16 High High
Inflammation 20 48.44 Quite Low
fibrosis 1 33.20 Quite Low
COX2 7 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 38 100.00 Very High Very High Very High
Infection 89 99.28 Very High Very High Very High
Viral Infection 3 93.12 High High
Respiratory Syncytial Virus 99 91.36 High High
Cv Unclassified Under Development 13 90.16 High High
Targeted Disruption 12 78.52 Quite High
Von Hippel-lindau Syndrome 1 71.52 Quite High
Sarcoma 2 68.16 Quite High
Sprains And Strains 3 57.76 Quite High
Cancer 5 57.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, such studies demonstrate a role for bacterial siderophores in hypoxia-independent activation of HIF-1?
Regulation (role) of Neg (independent) Positive_regulation (activation) of HIF-1 associated with hypoxia
1) Confidence 0.23 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2556398 Disease Relevance 1.15 Pain Relevance 0
This also allows us to investigate the effects of enhancing HIF-1 activity in the adult animal, avoiding any developmental effects, and modeling the potential use of HIF-1?
Spec (investigate) Regulation (effects) of Positive_regulation (enhancing) of HIF-1
2) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908132 Disease Relevance 0.49 Pain Relevance 0.05

General Comments

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