INT247565

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Context Info
Confidence 0.22
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 4.04
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Fn1) cell adhesion (Fn1) proteinaceous extracellular matrix (Fn1)
extracellular matrix organization (Fn1)
Anatomy Link Frequency
epithelial cells 4
Fn1 (Mus musculus)
Pain Link Frequency Relevance Heat
COX2 14 99.56 Very High Very High Very High
Inflammation 65 92.00 High High
fibrosis 7 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 178 99.56 Very High Very High Very High
Respiratory Syncytial Virus 198 99.16 Very High Very High Very High
INFLAMMATION 65 92.00 High High
Burns 10 80.32 Quite High
Hypoxia 50 76.44 Quite High
Keloid Scars 4 74.20 Quite High
Repression 14 38.08 Quite Low
Disease 9 5.00 Very Low Very Low Very Low
Fibrosis 8 5.00 Very Low Very Low Very Low
Pneumonia 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, we measured transcript levels of CD73 [62], VEGF [63], Fibronectin1 (FN1) [64] and COX2 [65] after 24 h of RSV infection of A549 pulmonary epithelial cells using different RSV infection doses (MOI1-5).
Negative_regulation (measured) of Negative_regulation (levels) of FN1 in epithelial cells associated with cox2, infection and respiratory syncytial virus
1) Confidence 0.22 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2556398 Disease Relevance 1.86 Pain Relevance 0.09
Thus, we measured transcript levels of CD73 [62], VEGF [63], Fibronectin1 (FN1) [64] and COX2 [65] after 24 h of RSV infection of A549 pulmonary epithelial cells using different RSV infection doses (MOI1-5).
Negative_regulation (measured) of Negative_regulation (levels) of Fibronectin1 in epithelial cells associated with cox2, infection and respiratory syncytial virus
2) Confidence 0.22 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2556398 Disease Relevance 1.86 Pain Relevance 0.09
Thus, we postulate that suppression of myofibroblasts by TSA is due to the suppression of Smad activity by the upregulation of Smad7 and TGIF and inhibition of extracellular deposition of fibronectin.
Negative_regulation (inhibition) of Negative_regulation (deposition) of fibronectin
3) Confidence 0.05 Published 2010 Journal Molecular Vision Section Body Doc Link PMC3013068 Disease Relevance 0.32 Pain Relevance 0.08

General Comments

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