INT247569

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Context Info
Confidence 0.48
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.15
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VEGFA) growth (VEGFA) extracellular region (VEGFA)
proteinaceous extracellular matrix (VEGFA) cytoplasm (VEGFA)
Anatomy Link Frequency
plasma 2
superior 2
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 33 76.04 Quite High
pain pelvic 2 28.96 Quite Low
cytokine 11 5.00 Very Low Very Low Very Low
COX2 7 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ectopic Pregnancy 95 99.84 Very High Very High Very High
Renal Cancer 63 99.84 Very High Very High Very High
Respiratory Syncytial Virus 99 99.76 Very High Very High Very High
Infection 94 99.60 Very High Very High Very High
Hypoxia 37 99.36 Very High Very High Very High
Repression 8 88.84 High High
Pathologic Neovascularization 2 83.12 Quite High
Coronary Heart Disease 1 82.92 Quite High
INFLAMMATION 32 76.04 Quite High
Diabetic Retinopathy 5 75.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, a 15-h period of daytime activity could elevate plasma concentrations to 42 pM and 1.1 pM above control for free sVEGFR1 and VEGF respectively.
Positive_regulation (elevate) of Regulation (control) of VEGF in plasma
1) Confidence 0.48 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0 Pain Relevance 0
Serum values of VEGF were significantly increased in EP, and a combination of three independent markers using the formula VEGF/(PAPP-A × Progesterone) was found to be superior to single marker measurements for discrimination between normal intrauterine pregnancy and EP (sensitivity of 97.7% and specificity of 92.4%).13

CREATINE KINASE (CK)

Positive_regulation (increased) of Regulation (values) of VEGF in superior associated with ectopic pregnancy
2) Confidence 0.45 Published 2008 Journal Clinics Section Body Doc Link PMC2664731 Disease Relevance 0.73 Pain Relevance 0
Inappropriate activation of the hypoxia response pathway, is the major mechanism of VEGF transcriptional regulation in renal cell carcinoma.2 The HIF?
Positive_regulation (mechanism) of Regulation (regulation) of VEGF associated with hypoxia and renal cancer
3) Confidence 0.37 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004565 Disease Relevance 0.55 Pain Relevance 0
B is essential for VEGF upward regulation induced by various stimuli [15].
Positive_regulation (induced) of Regulation (regulation) of VEGF
4) Confidence 0.25 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2830023 Disease Relevance 0.28 Pain Relevance 0
However, there are increasing examples that IGF-1 indirectly increases angiogenesis by up-regulation of VEGF (22, 25, 35).
Positive_regulation (increasing) of Regulation (regulation) of VEGF
5) Confidence 0.18 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2820781 Disease Relevance 0.50 Pain Relevance 0
-regulated genes (VEGF, CD73, FN-1, COX-2) were induced with RSV infection of wild-type cells.
Positive_regulation (induced) of Regulation (regulated) of VEGF associated with infection and respiratory syncytial virus
6) Confidence 0.09 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2556398 Disease Relevance 2.08 Pain Relevance 0.07

General Comments

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