INT247574

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Ube2e3, Hif1a) nucleus (Ube2e3, Hif1a) cytoplasm (Ube2e3, Hif1a)
cell differentiation (Hif1a) signal transduction (Hif1a) protein binding transcription factor activity (Hif1a)
Ube2e3 (Mus musculus)
Hif1a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 20 5.00 Very Low Very Low Very Low
COX2 7 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 3 98.94 Very High Very High Very High
Hypoxia 25 97.04 Very High Very High Very High
Respiratory Syncytial Virus 99 71.20 Quite High
Infection 89 70.84 Quite High
INFLAMMATION 20 5.00 Very Low Very Low Very Low
Repression 7 5.00 Very Low Very Low Very Low
Pneumonia 4 5.00 Very Low Very Low Very Low
Viral Infection 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Hepatitis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The modification is required for the binding of the von Hippel-Lindau (VHL) tumor suppressor protein, the recognition component of an E3 ubiquitin-protein ligase that targets HIF-1?
E3 ubiquitin-protein ligase Positive_regulation (targets) of HIF-1 associated with cancer
1) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2556398 Disease Relevance 0.62 Pain Relevance 0

General Comments

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