INT247599

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tlr4, App) plasma membrane (Tlr4, App) Golgi apparatus (App)
intracellular (Tlr4) extracellular matrix organization (App) DNA binding (App)
Tlr4 (Mus musculus)
App (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 58 98.08 Very High Very High Very High
Hippocampus 12 95.52 Very High Very High Very High
cytokine 10 75.68 Quite High
Inflammatory stimuli 2 22.56 Low Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 63 98.08 Very High Very High Very High
Cognitive Disorder 18 50.00 Quite Low
Alzheimer's Dementia 9 50.00 Quite Low
Cancer 3 33.20 Quite Low
Necrosis 2 32.72 Quite Low
Disease 24 5.00 Very Low Very Low Very Low
Death 16 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Amyloid Plaque 4 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, LPS treatment increased expression of APP, BACE and C99 accompanied with the increase of inflammatory proteins iNOS and COX-2 expression (Fig. 3D).


LPS Positive_regulation (increased) of Gene_expression (expression) of APP associated with inflammation
1) Confidence 0.17 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2556656 Disease Relevance 0.39 Pain Relevance 0.42

General Comments

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