INT247636

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.14
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Atf3) nucleus (Atf3) DNA binding (Atf3)
Anatomy Link Frequency
nerve 2
Atf3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 58 93.60 High High
cytokine 14 69.60 Quite High
Inflammation 13 59.88 Quite High
Peripheral nerve injury 13 54.12 Quite High
Neuropathic pain 27 50.00 Quite Low
Sciatic nerve 31 49.92 Quite Low
intrathecal 12 45.92 Quite Low
Thermal hyperalgesia 7 25.20 Quite Low
allodynia 7 24.20 Low Low
Potency 1 5.60 Low Low
Disease Link Frequency Relevance Heat
Injury 42 99.72 Very High Very High Very High
Nervous System Injury 60 99.04 Very High Very High Very High
Targeted Disruption 3 96.76 Very High Very High Very High
Apoptosis 6 87.48 High High
Disease 2 80.44 Quite High
Neurodegenerative Disease 2 78.36 Quite High
Death 2 64.84 Quite High
INFLAMMATION 22 59.88 Quite High
Neuropathic Pain 38 50.00 Quite Low
Hypersensitivity 14 45.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Outgrowing axons were associated with ATF3 stained Schwann cells in the distal nerve segment [14] (Figure 3).
ATF3 Binding (associated) of in nerve
1) Confidence 0.36 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2556676 Disease Relevance 0 Pain Relevance 0
ATF3 is a member of the activating transcription factor/cAMP-responsive element binding protein family (ATF/CREB family) and is recognized as a useful marker for nerve injury.
ATF3 Binding (recognized) of in nerve associated with nervous system injury
2) Confidence 0.30 Published 2009 Journal Mol Pain Section Body Doc Link PMC2669449 Disease Relevance 1.14 Pain Relevance 0.27

General Comments

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