INT247730

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Context Info
Confidence 0.18
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.37
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Rarres2)
Anatomy Link Frequency
leukocytes 1
Rarres2 (Mus musculus)
Pain Link Frequency Relevance Heat
Bioavailability 2 100.00 Very High Very High Very High
chemokine 66 96.76 Very High Very High Very High
Inflammation 16 5.00 Very Low Very Low Very Low
cytokine 12 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaphylaxis 58 86.08 High High
Hypersensitivity 4 80.56 Quite High
Edema 38 74.96 Quite High
INFLAMMATION 22 5.00 Very Low Very Low Very Low
Contact Dermatitis 14 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We hypothesize, therefore, that CCRL2 serves a novel role among cell surface chemoattractant receptors, regulating the bioavailability of chemerin in vivo to fine-tune immune responses mediated via the signaling receptor CMKLR1.
Regulation (regulating) of chemerin associated with bioavailability
1) Confidence 0.18 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556791 Disease Relevance 0 Pain Relevance 0.05
In its role as a specialized molecule for concentrating extracellular chemerin, CCRL2 may operate akin to glycosaminoglycans, which are thought to bind, concentrate, and present chemokines to leukocytes and facilitate their chemotaxis (38).
Spec (may) Regulation (operate) of chemerin in leukocytes associated with chemokine
2) Confidence 0.08 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556791 Disease Relevance 0.37 Pain Relevance 0.07

General Comments

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