INT247739

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ccbp2) plasma membrane (Ccbp2) signal transducer activity (Ccbp2)
Anatomy Link Frequency
leukocytes 1
Ccbp2 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 66 99.20 Very High Very High Very High
rheumatoid arthritis 2 40.60 Quite Low
agonist 2 38.76 Quite Low
Inflammatory response 6 23.92 Low Low
Inflammation 16 22.28 Low Low
Multiple sclerosis 2 11.72 Low Low
cytokine 12 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 2 40.60 Quite Low
INFLAMMATION 22 23.92 Low Low
Disease 4 14.88 Low Low
Demyelinating Disease 2 11.72 Low Low
Multiple Sclerosis 2 10.20 Low Low
Anaphylaxis 58 5.00 Very Low Very Low Very Low
Edema 38 5.00 Very Low Very Low Very Low
Contact Dermatitis 14 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data place CCRL2 in a class of atypical receptors that include D6, DARC, and CCX-CKR, all of which bind to chemoattractants but do not support classical ligand-driven signal transduction (for review see reference 11).
D6 Neg (not) Binding (bind) of
1) Confidence 0.11 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556791 Disease Relevance 0 Pain Relevance 0.08
D6 is expressed by lymphatic endothelium and by some leukocytes and binds proinflammatory CC chemokines.
D6 Binding (binds) of in leukocytes associated with chemokine
2) Confidence 0.09 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556791 Disease Relevance 0 Pain Relevance 0.45

General Comments

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