INT247755

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.53
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cmklr1, Ccrl2) plasma membrane (Cmklr1, Ccrl2) signal transducer activity (Cmklr1, Ccrl2)
Cmklr1 (Mus musculus)
Ccrl2 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 66 96.04 Very High Very High Very High
Inflammation 16 84.76 Quite High
Inflammatory response 6 71.68 Quite High
cytokine 12 35.60 Quite Low
Potency 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 22 84.76 Quite High
Edema 38 84.72 Quite High
Anaphylaxis 58 67.68 Quite High
Hemorrhage 2 5.60 Low Low
Contact Dermatitis 14 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rather, CCRL2 concentrates the chemoattractant and increases local chemerin concentrations available to interact with CMKLR1.
CMKLR1 Binding (interact) of CCRL2
1) Confidence 0.05 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556791 Disease Relevance 0.53 Pain Relevance 0.17
The binding affinity of chemerin for CCRL2 was similar to, if not slightly better than, chemerin binding to the first identified chemerin receptor, mCMKLR1 (EC50 = 3.1 nM; Fig. 6 B).
mCMKLR1 Binding (binding) of CCRL2
2) Confidence 0.05 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556791 Disease Relevance 0 Pain Relevance 0

General Comments

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