INT247758

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Context Info
Confidence 0.25
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.87
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ccrl2) extracellular region (Rarres2) plasma membrane (Ccrl2)
signal transducer activity (Ccrl2)
Ccrl2 (Mus musculus)
Rarres2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 16 97.88 Very High Very High Very High
chemokine 66 96.68 Very High Very High Very High
Inflammatory response 6 71.68 Quite High
cytokine 12 35.60 Quite Low
Potency 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 22 97.88 Very High Very High Very High
Edema 38 87.72 High High
Anaphylaxis 58 86.28 High High
Hemorrhage 2 5.60 Low Low
Contact Dermatitis 14 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rather, CCRL2 concentrates the chemoattractant and increases local chemerin concentrations available to interact with CMKLR1.
CCRL2 Positive_regulation (increases) of chemerin
1) Confidence 0.25 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556791 Disease Relevance 0.53 Pain Relevance 0.17
Rather, CCRL2 is able to bind the chemoattractant and increase local concentrations of bioactive chemerin, thus providing a link between CCRL2 expression and inflammation via the cell-signaling chemerin receptor CMKLR1.



CCRL2 Positive_regulation (increase) of chemerin associated with inflammation
2) Confidence 0.25 Published 2008 Journal The Journal of Experimental Medicine Section Abstract Doc Link PMC2556791 Disease Relevance 0.35 Pain Relevance 0.10

General Comments

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