INT247820

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Gjc1, Gja5) cell-cell signaling (Gjc1, Gja5)
Anatomy Link Frequency
CAR 1
Gjc1 (Mus musculus)
Gja5 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 1 39.08 Quite Low
anesthesia 6 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 75 99.52 Very High Very High Very High
Heart Rate Under Development 5 81.84 Quite High
Arrhythmias 2 Under Development 4 58.48 Quite High
Arrhythmia Under Development 19 51.04 Quite High
Congenital Anomalies 1 9.60 Low Low
Disease 7 5.00 Very Low Very Low Very Low
Heart Disease 3 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Embryonic Lethality 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Together with the functional analysis indicating that Cx40 or Cx45 are affected in the CAR KO (both share the AV block phenotype with the CAR KO), the expression analysis suggests that the effect of CAR is mediated by Cx45.
Cx45 Regulation (affected) of Cx40 in CAR associated with targeted disruption
1) Confidence 0.08 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556793 Disease Relevance 1.24 Pain Relevance 0

General Comments

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