INT247823

Context Info Confidence 0.08 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.40 Pain Relevance 0

cytoplasm (Cxadr, Tjp1) nucleus (Cxadr, Tjp1) plasma membrane (Cxadr, Tjp1) Golgi apparatus (Tjp1) mitochondrion organization (Cxadr) protein complex (Cxadr)

Anatomy Link Frequency CAR 1 Cxadr (Mus musculus) Tjp1 (Mus musculus)

Pain Link Frequency Relevance Heat anesthesia 6 5.00 addiction 1 5.00 fibrosis 1 5.00 isoflurane 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 75 92.16 Arrhythmia Under Development 19 85.84 Disease 7 25.60 Heart Rate Under Development 5 5.00 Arrhythmias 2 Under Development 4 5.00 Heart Disease 3 5.00 Pressure And Volume Under Development 2 5.00 Embryonic Lethality 2 5.00 Body Weight 2 5.00 Infection 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This includes reduced expression of ZO-1, an adaptor protein that binds both CAR and connexins (Fig. 6 A) (8, 21).

CAR Binding (binds) of ZO-1 in CAR

1) Confidence 0.08 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556793 Disease Relevance 0.40 Pain Relevance 0

General Comments

This test has worked.