INT247860

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.46
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Uchl1) intracellular (Uchl1) ligase activity (Uchl1)
response to stress (Uchl1) cytoplasm (Uchl1) cell proliferation (Uchl1)
Anatomy Link Frequency
retina 1
Uchl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
glial activation 2 38.32 Quite Low
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
hyperexcitability 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ocular Hypertension 150 98.40 Very High Very High Very High
Injury 24 93.04 High High
Disease 6 71.24 Quite High
Ganglion Cysts 12 68.32 Quite High
Stress 8 67.20 Quite High
Glaucoma 36 67.12 Quite High
Hypertrophy 16 29.12 Quite Low
Low Tension Glaucoma 4 26.96 Quite Low
Targeted Disruption 4 8.96 Low Low
Neurodegenerative Disease 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although the downregulation of ubiquitin hydrolase may explain the enhanced ubiquitination in retina, UCH-L1 protein levels did not change significantly in retinas with elevated IOP (data not shown).
Neg (not) Regulation (change) of UCH-L1 protein in retina associated with ocular hypertension
1) Confidence 0.14 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2559817 Disease Relevance 0.65 Pain Relevance 0
Real-time quantitative PCR (Q-PCR) was used for measuring changes in AQP4, ubiquitin hydrolase L1 (UCH-L1), and ?
Regulation (changes) of ubiquitin hydrolase L1
2) Confidence 0.06 Published 2008 Journal Molecular Vision Section Abstract Doc Link PMC2559817 Disease Relevance 0.81 Pain Relevance 0

General Comments

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