INT247903

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 5.69
Pain Relevance 1.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGA1) plasma membrane (ITGA1)
Anatomy Link Frequency
macrophages 1
natural killer cells 1
mast cells 1
ITGA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 18 100.00 Very High Very High Very High
Inflammatory response 9 99.92 Very High Very High Very High
Inflammation 15 90.52 High High
chemokine 6 80.20 Quite High
fibrosis 24 66.64 Quite High
depression 6 42.48 Quite Low
methotrexate 39 5.00 Very Low Very Low Very Low
Arthritis 27 5.00 Very Low Very Low Very Low
corticosteroid 18 5.00 Very Low Very Low Very Low
rheumatoid arthritis 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 6 100.00 Very High Very High Very High
INFLAMMATION 24 99.74 Very High Very High Very High
Disease 138 92.92 High High
Granuloma 66 92.04 High High
Sarcoidosis 411 85.24 High High
Pulmonary Disease 18 68.04 Quite High
Fibrosis 21 66.64 Quite High
Necrosis 3 56.32 Quite High
Cancer 6 55.96 Quite High
Congenital Anomalies 12 55.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The CD4+ lymphocytes, in association with other immune effector cells, such as macrophages, mast cells, and natural killer cells, perpetuate the inflammatory response by release of cytokines, monocyte chemotactic factors, macrophage migration inhibitory factor, leukocyte inhibitory factor, adhesion molecules (CD49a, CD54, CD102), and growth factors [35,36].
Localization (release) of CD49a in mast cells associated with inflammatory response, adhesions and cytokine
1) Confidence 0.06 Published 2008 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2559831 Disease Relevance 1.90 Pain Relevance 0.44
The CD4+ lymphocytes, in association with other immune effector cells, such as macrophages, mast cells, and natural killer cells, perpetuate the inflammatory response by release of cytokines, monocyte chemotactic factors, macrophage migration inhibitory factor, leukocyte inhibitory factor, adhesion molecules (CD49a, CD54, CD102), and growth factors [35,36].
Localization (release) of CD49a in natural killer cells associated with inflammatory response, adhesions and cytokine
2) Confidence 0.02 Published 2008 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2559831 Disease Relevance 1.90 Pain Relevance 0.44
The CD4+ lymphocytes, in association with other immune effector cells, such as macrophages, mast cells, and natural killer cells, perpetuate the inflammatory response by release of cytokines, monocyte chemotactic factors, macrophage migration inhibitory factor, leukocyte inhibitory factor, adhesion molecules (CD49a, CD54, CD102), and growth factors [35,36].
Localization (release) of CD49a in macrophages associated with inflammatory response, adhesions and cytokine
3) Confidence 0.02 Published 2008 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2559831 Disease Relevance 1.90 Pain Relevance 0.44

General Comments

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