INT247924

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Context Info
Confidence 0.25
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.43
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Slc12a5, Slc12a2) intracellular (Slc12a5) transmembrane transport (Slc12a5)
Anatomy Link Frequency
spinal cords 2
Slc12a5 (Rattus norvegicus)
Slc12a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
GABAergic 8 91.64 High High
Inflammation 1 90.32 High High
Neuropathic pain 18 90.24 High High
Peripheral nerve injury 1 86.12 High High
Hyperalgesia 14 84.76 Quite High
agonist 1 82.36 Quite High
allodynia 3 78.00 Quite High
gABA 4 75.84 Quite High
Dorsal horn 3 72.52 Quite High
Spinal cord 26 70.16 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 1 90.32 High High
Neuropathic Pain 26 90.24 High High
Nervous System Injury 4 86.12 High High
Hyperalgesia 42 84.76 Quite High
Hypersensitivity 2 82.40 Quite High
Injury 12 79.84 Quite High
Nociception 7 73.72 Quite High
Spinal Cord Injury 72 65.60 Quite High
Pain 5 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both NKCC1 and KCC2 are expressed in spinal cords and function to regulate intracellular Cl- concentration.
KCC2 Regulation (regulate) of Gene_expression (expressed) of NKCC1 in spinal cords
1) Confidence 0.25 Published 2008 Journal Mol Pain Section Body Doc Link PMC2561007 Disease Relevance 1.43 Pain Relevance 1.23

General Comments

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