INT247999

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.75
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (FXYD1)
FXYD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 10 96.80 Very High Very High Very High
anticonvulsant 1 81.64 Quite High
Paresthesia 1 16.48 Low Low
Dopamine 19 5.00 Very Low Very Low Very Low
agonist 19 5.00 Very Low Very Low Very Low
peripheral neuropathy 8 5.00 Very Low Very Low Very Low
transdermal 6 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Restless Legs Syndrome 168 99.22 Very High Very High Very High
Pain 3 96.80 Very High Very High Very High
Akathisia 16 95.80 Very High Very High Very High
Sleep-wake Transition Disorders 1 95.28 Very High Very High Very High
Sleep Disorders 25 91.20 High High
Leukemia 1 89.64 High High
Hematological Disease 44 79.00 Quite High
Cramps 2 75.12 Quite High
Myoclonus 1 68.60 Quite High
Death 3 61.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, similarly to RLS, dopaminergic agents are effective in decreasing PLM number.


Negative_regulation (decreasing) of PLM associated with restless legs syndrome
1) Confidence 0.06 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695234 Disease Relevance 1.19 Pain Relevance 0.35
54 of 54; 100%) were reduced in the ALM and PLM of the zTERT morphants (Figure 3A, a–f, a'–d') at 19 hpf, but almost recovered at the normal levels by 24 hpf (data not shown).
Negative_regulation (reduced) of PLM
2) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2561060 Disease Relevance 0.57 Pain Relevance 0

General Comments

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