INT248200

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Context Info
Confidence 0.51
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Disc1) endoplasmic reticulum (Disc1) cytoskeleton (Disc1)
nucleus (Disc1) cytoplasm (Disc1)
Anatomy Link Frequency
neuronal 1
Disc1 (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 2 41.24 Quite Low
imagery 3 7.28 Low Low
Hippocampus 24 5.00 Very Low Very Low Very Low
Eae 18 5.00 Very Low Very Low Very Low
Dopamine 7 5.00 Very Low Very Low Very Low
Action potential 3 5.00 Very Low Very Low Very Low
amygdala 2 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 35 100.00 Very High Very High Very High
Neurodegenerative Disease 8 80.12 Quite High
Mental Disorders 4 57.76 Quite High
Manic Depressive Disorder 7 50.88 Quite High
Disease 1 6.52 Low Low
Congenital Anomalies 7 5.00 Very Low Very Low Very Low
Anxiety Disorder 7 5.00 Very Low Very Low Very Low
Shock 5 5.00 Very Low Very Low Very Low
Sprains And Strains 5 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, it was reported that Disc1, a susceptibility gene for schizophrenia, is highly expressed in DG in adulthood [52,53] and is important for organizing newly generated as well as mature neurons and for regulating the neuronal integration in the DG, which may contribute to the pathophysiology of psychiatric disorders conferred by this gene [54,55].
Gene_expression (expressed) of Disc1 in neuronal associated with schizophrenia
1) Confidence 0.51 Published 2008 Journal Mol Brain Section Body Doc Link PMC2562999 Disease Relevance 0.54 Pain Relevance 0

General Comments

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