INT248227

Context Info Confidence 0.46 First Reported 2008 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 4 Total Number 4 Disease Relevance 2.48 Pain Relevance 0.77

peptidase activity (CFD) extracellular space (CFD) extracellular region (CFD)

Anatomy Link Frequency myocardium 1 CFD (Homo sapiens)

Pain Link Frequency Relevance Heat Nicotine 79 97.48 addiction 190 82.60 imagery 14 79.56 Inflammation 34 78.60 rheumatoid arthritis 3 47.52 antagonist 3 45.20 Pain 1 34.08 fibrosis 55 28.76 alcohol 21 5.00 cocaine 8 5.00

Disease Link Frequency Relevance Heat Keloid Scars 9 99.24 Injury 11 93.44 Cicatrix 4 93.20 Death 9 85.48 Drug Dependence 100 82.60 INFLAMMATION 32 78.60 Burns 2 77.52 Disease 89 71.00 Contracture 1 69.08 Fibrosis 50 65.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

PFD may cause increased degradation and absorption of keloid tissue [69].

Protein_catabolism (degradation) of PFD associated with keloid scars

1) Confidence 0.46 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2944211 Disease Relevance 1.60 Pain Relevance 0.04

nAChRs activation promotes survival of DF+hESC-EC in ischemic myocardium

Protein_catabolism (survival) of DF+hESC-EC in myocardium

2) Confidence 0.26 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2737633 Disease Relevance 0.09 Pain Relevance 0.52

One reason is that, from a statistical perspective, the HWD test in cases has one degree of freedom (df = 1), rather than df = 2 for case-control genotype frequency comparisons.

Protein_catabolism (degree) of df

3) Confidence 0.07 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2563013 Disease Relevance 0.39 Pain Relevance 0.10

One reason is that, from a statistical perspective, the HWD test in cases has one degree of freedom (df = 1), rather than df = 2 for case-control genotype frequency comparisons.

Protein_catabolism (degree) of df

4) Confidence 0.07 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2563013 Disease Relevance 0.40 Pain Relevance 0.10

General Comments

This test has worked.