INT248253

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 4.61
Pain Relevance 1.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (HSPG2) small molecule metabolic process (HSPG2) extracellular region (HSPG2)
plasma membrane (HSPG2) extracellular matrix organization (HSPG2) lipid metabolic process (HSPG2)
HSPG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 39 99.20 Very High Very High Very High
antiepileptic Drug 1 99.16 Very High Very High Very High
Arthritis 38 99.00 Very High Very High Very High
cINOD 1 96.00 Very High Very High Very High
Lamotrigine 1 94.24 High High
carbamazepine 1 93.56 High High
Inflammation 8 92.00 High High
anticonvulsant 1 91.32 High High
corticosteroid 13 89.04 High High
medial meniscus tear 6 73.20 Quite High
Disease Link Frequency Relevance Heat
Syndrome 19 100.00 Very High Very High Very High
Osteoarthritis 26 99.84 Very High Very High Very High
Rheumatoid Arthritis 39 99.20 Very High Very High Very High
Seronegative Spondarthritis 24 99.00 Very High Very High Very High
INFLAMMATION 10 95.76 Very High Very High Very High
Injury 174 85.76 High High
Staphylococcus Infection 21 84.20 Quite High
Disease 8 79.68 Quite High
Cicatrix 9 79.08 Quite High
Adverse Drug Reaction 8 78.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following McGuire’s technique [9], a single femoral tunnel was performed on four patients, while in the remaining six patients, the reconstruction of the PLC was performed with a double femoral tunnel, as described by Arciero [10] (Figs. 1, 2).Fig. 1Single femoral tunnel technique, as described by McGuireFig. 2Double femoral tunnel following Arciero’s technique
Positive_regulation (reconstruction) of Gene_expression (reconstruction) of PLC
1) Confidence 0.44 Published 2010 Journal J Orthop Traumatol Section Body Doc Link PMC2896579 Disease Relevance 0.44 Pain Relevance 0.13
Following McGuire’s technique [9], a single femoral tunnel was performed on four patients, while in the remaining six patients, the reconstruction of the PLC was performed with a double femoral tunnel, as described by Arciero [10] (Figs. 1, 2).Fig. 1Single femoral tunnel technique, as described by McGuireFig. 2Double femoral tunnel following Arciero’s technique
Positive_regulation (Following) of Gene_expression (reconstruction) of PLC
2) Confidence 0.44 Published 2010 Journal J Orthop Traumatol Section Body Doc Link PMC2896579 Disease Relevance 0.48 Pain Relevance 0.19
Following McGuire’s technique [9], a single femoral tunnel was performed on four patients, while in the remaining six patients, the reconstruction of the PLC was performed with a double femoral tunnel, as described by Arciero [10] (Figs. 1, 2).Fig. 1Single femoral tunnel technique, as described by McGuireFig. 2Double femoral tunnel following Arciero’s technique
Positive_regulation (performed) of Gene_expression (reconstruction) of PLC
3) Confidence 0.44 Published 2010 Journal J Orthop Traumatol Section Body Doc Link PMC2896579 Disease Relevance 0.44 Pain Relevance 0.13
Similarly the level of HSPG expression was lowest in normal synovia and increased in OA, followed by RA and PsA.
Positive_regulation (increased) of Gene_expression (expression) of HSPG associated with rheumatoid arthritis, osteoarthritis and arthritis
4) Confidence 0.32 Published 2008 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2563418 Disease Relevance 1.74 Pain Relevance 0.80
HLA B*38 showed only a weak association with sulfamethoxazole induced SJS/TEN54 in contrast to antiepileptic drugs and allopurinol where HLA associations are stronger and ethnically related.112
Positive_regulation (induced) of Gene_expression (/) of SJS associated with syndrome and antiepileptic drug
5) Confidence 0.16 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2846744 Disease Relevance 1.51 Pain Relevance 0.40

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