INT248303

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Context Info
Confidence 0.61
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.06
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Crx) DNA binding (Crx)
Crx (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 24 100.00 Very High Very High Very High
Arthritis 4 95.44 Very High Very High Very High
Osteoarthritis 84 90.76 High High
Pain 44 81.08 Quite High
backache 2 72.64 Quite High
adenocard 6 31.84 Quite Low
headache 16 31.52 Quite Low
Pain scale 22 5.00 Very Low Very Low Very Low
cINOD 14 5.00 Very Low Very Low Very Low
corticosteroid 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 26 100.00 Very High Very High Very High
Cancer 2 97.16 Very High Very High Very High
Necrosis 2 96.88 Very High Very High Very High
Arthritis 4 95.44 Very High Very High Very High
Osteoarthritis 40 90.76 High High
Disease 26 90.20 High High
Pain 38 81.08 Quite High
Arthralgia 10 79.72 Quite High
Low Back Pain 2 72.64 Quite High
Osteoarthropathy 44 57.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CRx-102 has been shown to have strong anti-inflammatory effects in preclinical assays with a greater average percentage inhibition of tumour necrosis factor alpha (TNF?)
Gene_expression (effects) of CRx-102 associated with necrosis, inflammation and cancer
1) Confidence 0.61 Published 2008 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2564788 Disease Relevance 1.18 Pain Relevance 0.60
release, the inhibition of release was greater with CRx-102 than the individual components.21 This finding was replicated in the rat models of adjuvant and collagen-induced arthritis.21
Gene_expression (greater) of CRx-102 associated with arthritis
2) Confidence 0.53 Published 2008 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2564788 Disease Relevance 0.88 Pain Relevance 0.44

General Comments

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