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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.90
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell-cell signaling (S100A9) cytoplasm (S100A9) signal transducer activity (S100A9)
signal transduction (S100A9) extracellular space (S100A9) extracellular region (S100A9)
Anatomy Link Frequency
macrophages 2
nasal 2
S100A9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 33 63.32 Quite High
rheumatoid arthritis 19 50.00 Quite Low
Infliximab 9 50.00 Quite Low
cytokine 13 28.48 Quite Low
Inflammatory response 2 25.76 Quite Low
chemokine 6 5.00 Very Low Very Low Very Low
aspirin 5 5.00 Very Low Very Low Very Low
methotrexate 5 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eosinophilic Esophagitis 5 98.08 Very High Very High Very High
Chronic Sinusitis 14 96.16 Very High Very High Very High
Rhinitis 62 94.96 High High
Disease 30 89.20 High High
Adhesions 14 77.64 Quite High
Eczema 31 77.04 Quite High
INFLAMMATION 36 63.32 Quite High
Asthma 17 56.20 Quite High
Anaphylaxis 1 51.84 Quite High
Rheumatoid Arthritis 19 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Decreased expression of S100A8 and S100A9, members of the epidermal differentiation complex at chromosome 1q21, in epithelial cells from CRS patients with and without nasal polyps was recently reported [35], [36].
Negative_regulation (Decreased) of Gene_expression (expression) of S100A9 in nasal associated with rhinitis and chronic sinusitis
1) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.82 Pain Relevance 0.03
in a bivariate logistic regression model including either the numbers of CD68+ sublining macrophages, CD163+, MPR8+, MRP14+ macrophages, or CD3+ T cells, these cellular markers were no longer significantly associated with response.
Negative_regulation (numbers) of Gene_expression (macrophages) of MRP14 in macrophages
2) Confidence 0.22 Published 2008 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2564801 Disease Relevance 0.08 Pain Relevance 0

General Comments

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