INT248401

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Context Info
Confidence 0.67
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 21
Total Number 21
Disease Relevance 14.52
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (CDKN1C) nucleus (CDKN1C) cell cycle (CDKN1C)
cytoplasm (CDKN1C)
Anatomy Link Frequency
hip 3
knee 3
ankle joints 2
limb 2
joint 1
CDKN1C (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 80 63.48 Quite High
Spinal cord 60 62.52 Quite High
Pain 21 42.80 Quite Low
backache 20 36.88 Quite Low
Multiple sclerosis 20 11.52 Low Low
addiction 4 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Beckwith-wiedemann Syndrome 1520 100.00 Very High Very High Very High
Adhesions 6 100.00 Very High Very High Very High
Aging 260 99.80 Very High Very High Very High
Cancer 101 99.30 Very High Very High Very High
Body Weight 260 97.36 Very High Very High Very High
Renal Cancer 55 90.52 High High
Injury 40 85.80 High High
Stroke 80 74.24 Quite High
Emergencies 20 61.60 Quite High
Pain 21 42.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At higher levels of BWS, a reduction of force at the knee might have resulted in less knee involvement.
Gene_expression (levels) of BWS in knee associated with beckwith-wiedemann syndrome
1) Confidence 0.67 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.82 Pain Relevance 0
With respect to the main effect of the BWS factor, significant differences were found for the hip ROM CV (F(3,54) = 4.9; p = 0.004) and the ankle ROM SD (F(3.54) = 3.2; p = 0.031) and CV (F(3,54) = 3.9; p = 0.012) (Figure 3).
Gene_expression (effect) of BWS factor in ankle associated with beckwith-wiedemann syndrome
2) Confidence 0.67 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.45 Pain Relevance 0
The subjects were given sufficient time to experience different levels of BWS, since it has been shown that there is a short accommodation period when walking in reduced gravity conditions [44].
Gene_expression (levels) of BWS associated with beckwith-wiedemann syndrome
3) Confidence 0.60 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 1.08 Pain Relevance 0
This outcome was attributed by these authors to the balance component of gait being stressed at higher levels of BWS.
Gene_expression (levels) of BWS associated with beckwith-wiedemann syndrome
4) Confidence 0.58 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.65 Pain Relevance 0
Another explanation may be the decreased role that limb loading plays at higher BWS levels.
Gene_expression (levels) of BWS in limb associated with beckwith-wiedemann syndrome
5) Confidence 0.58 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.65 Pain Relevance 0
Specifically, our results differ from Threlkeld et al. [47] who found minimal variability in hip motion at comparable levels of BWS, while our findings agree with those reported by Finch et al. [61] who found variability in the hip angle to be significantly more at 30% as compared to 10% BWS.
Gene_expression (levels) of BWS in hip associated with beckwith-wiedemann syndrome
6) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.52 Pain Relevance 0
Increased levels of BWS increased lower extremity kinematic variability.
Gene_expression (levels) of BWS in extremity associated with beckwith-wiedemann syndrome
7) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Abstract Doc Link PMC2564959 Disease Relevance 0.84 Pain Relevance 0
In order to minimize the vest shifting up the torso with increased levels of BWS, air was hand-pumped into the right and left chambers of the vest until it was comfortably tight.
Gene_expression (levels) of BWS associated with beckwith-wiedemann syndrome
8) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.42 Pain Relevance 0
Therefore, the purpose of this study was to determine the kinematic variability of the lower extremities in young and elderly healthy females at changing levels of BWS during walking.
Gene_expression (levels) of BWS associated with beckwith-wiedemann syndrome
9) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.67 Pain Relevance 0.03
Overall our results refuted our first hypothesis showing that increased levels of BWS resulted in increased variability.
Gene_expression (levels) of BWS associated with beckwith-wiedemann syndrome
10) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.77 Pain Relevance 0
It was hypothesized that increased levels of BWS would decrease both linear and nonlinear measures of angular kinematic variability of the hip, knee and ankle joints.
Gene_expression (levels) of BWS in hip associated with beckwith-wiedemann syndrome
11) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.51 Pain Relevance 0.03
For the next minute, various levels of BWS were applied to allow the subject to experience mechanical uploading of body weight.
Gene_expression (levels) of BWS in body associated with beckwith-wiedemann syndrome and body weight
12) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 1.05 Pain Relevance 0
In the present study, we found that different levels of BWS and aging affected angular kinematic variability of the hip, knee and ankle joints.
Gene_expression (levels) of BWS in ankle joints associated with beckwith-wiedemann syndrome and aging
13) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.52 Pain Relevance 0.03
Increased levels of BWS resulted in increased linear and nonlinear measures of joint kinematic variability.
Gene_expression (levels) of BWS in joint associated with beckwith-wiedemann syndrome
14) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.52 Pain Relevance 0.03
It was hypothesized that increased levels of BWS would decrease both linear and nonlinear measures of angular kinematic variability of the hip, knee and ankle joints.
Gene_expression (levels) of BWS in angular associated with beckwith-wiedemann syndrome
15) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 1.03 Pain Relevance 0
The purpose of this study was to determine the kinematic variability of the lower extremities in young and elderly healthy females at changing levels of BWS during walking.
Gene_expression (levels) of BWS associated with beckwith-wiedemann syndrome
16) Confidence 0.52 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 1.16 Pain Relevance 0
These include the oncogenes JAZF1, AXL, ABL2; tumor suppressors RASD1, PTPRO, TFAP2A, CDKN1C; and genes involved in proteolysis or cell-adhesion such as WASF2, and PAPPA.



Gene_expression (adhesion) of CDKN1C associated with cancer and adhesions
17) Confidence 0.47 Published 2007 Journal Cancer Informatics Section Abstract Doc Link PMC2675843 Disease Relevance 0.83 Pain Relevance 0
In the present study, we found that different levels of BWS and aging affected angular kinematic variability of the hip, knee and ankle joints.
Gene_expression (levels) of BWS in hip associated with beckwith-wiedemann syndrome and aging
18) Confidence 0.18 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.52 Pain Relevance 0.03
It was hypothesized that increased levels of BWS would decrease both linear and nonlinear measures of angular kinematic variability of the hip, knee and ankle joints.
Gene_expression (levels) of BWS in ankle joints associated with beckwith-wiedemann syndrome
19) Confidence 0.18 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.51 Pain Relevance 0.03
It was hypothesized that increased levels of BWS would decrease both linear and nonlinear measures of angular kinematic variability of the hip, knee and ankle joints.
Gene_expression (levels) of BWS in knee associated with beckwith-wiedemann syndrome
20) Confidence 0.18 Published 2008 Journal J Neuroeng Rehabil Section Body Doc Link PMC2564959 Disease Relevance 0.51 Pain Relevance 0.03

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