INT248421

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Tph1)
Anatomy Link Frequency
brain 1
Tph1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 6 89.00 High High
5HT 1 82.80 Quite High
Antinociceptive 1 79.52 Quite High
fluoxetine 1 78.36 Quite High
sSRI 4 77.88 Quite High
Neuropathic pain 1 74.36 Quite High
Migraine 1 73.52 Quite High
Analgesic 2 72.12 Quite High
antidepressant 16 70.24 Quite High
Inflammation 1 68.72 Quite High
Disease Link Frequency Relevance Heat
Pain 6 89.00 High High
Targeted Disruption 92 83.04 Quite High
Neuropathic Pain 1 74.36 Quite High
Headache 1 73.52 Quite High
Nervous System Injury 1 69.40 Quite High
INFLAMMATION 1 68.72 Quite High
Hyperalgesia 2 68.08 Quite High
Nociception 4 59.08 Quite High
Congenital Anomalies 3 39.60 Quite Low
Sprains And Strains 1 21.20 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This is consistent with evidence that TPH2 is the primary synthetic enzyme in the brain, while TPH1 is responsible for 5-HT synthesis in extraneuronal tissues.
Regulation (responsible) of TPH1 in brain
1) Confidence 0.27 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565062 Disease Relevance 0.89 Pain Relevance 0.87

General Comments

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