From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.05
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.96
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (Ighmbp2) nucleus (Ighmbp2) DNA binding (Ighmbp2)
transcription factor binding (Ighmbp2) cytoplasm (Ighmbp2)
Ighmbp2 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 1 50.04 Quite High
Intracerebroventricular 2 7.20 Low Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Spinal Muscular Atrophy 32 100.00 Very High Very High Very High
Death 1 79.28 Quite High
Neurodegenerative Disease 1 74.48 Quite High
Targeted Disruption 7 69.44 Quite High
Frailty 1 55.28 Quite High
Epidermolysis Bullosa Simplex 1 54.32 Quite High
Disease 6 52.92 Quite High
Coagulation Disorder 1 52.00 Quite High
Immunodeficiency 1 51.52 Quite High
Cystic Fibrosis 1 50.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SMN2 is retained in essentially all SMA patients and is a primary target for SMA therapeutic development [13].
Regulation (target) of SMA associated with spinal muscular atrophy
1) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565107 Disease Relevance 0.96 Pain Relevance 0.03
Specifically, we showed that Haplotype A-derived mRNA encodes full-length, canonical ERAP2, while Haplotype B-derived mRNA undergoes differential splicing and NMD, resulting in undetectable levels of ERAP2.
Regulation (derived) of NMD
2) Confidence 0.03 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2954825 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools