INT248492

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Upf1, Smn1) RNA binding (Upf1, Smn1) helicase activity (Upf1)
DNA binding (Upf1) nucleolus (Smn1) mRNA processing (Smn1)
Anatomy Link Frequency
HeLa 1
Upf1 (Mus musculus)
Smn1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Intracerebroventricular 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Spinal Muscular Atrophy 32 79.52 Quite High
Disease 6 67.84 Quite High
Coagulation Disorder 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Frailty 1 5.00 Very Low Very Low Very Low
Immunodeficiency 1 5.00 Very Low Very Low Very Low
Epidermolysis Bullosa Simplex 1 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low
Cystic Fibrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with the co-transfections, the single pMU3 vector resulted in high levels of SMN trans-splicing between endogenous HeLa cell SMN transcripts.
transcripts Positive_regulation (levels) of SMN in HeLa
1) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565107 Disease Relevance 0.15 Pain Relevance 0

General Comments

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