INT248539

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.31
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.28
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pou5f1) nucleoplasm (Pou5f1) nucleus (Pou5f1)
DNA binding (Pou5f1) transcription factor binding (Pou5f1) cytoplasm (Pou5f1)
Anatomy Link Frequency
stem cells 2
Pou5f1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 21 5.00 Very Low Very Low Very Low
Action potential 11 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 72 98.68 Very High Very High Very High
Glioblastoma 18 94.40 High High
Teratoma 10 94.08 High High
Malignant Neoplastic Disease 5 91.20 High High
Death 7 90.40 High High
Stress 10 89.76 High High
Glioma 45 89.20 High High
Brain Tumor 60 73.28 Quite High
Apoptosis 30 5.00 Very Low Very Low Very Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our microarray analysis, we observed high expression of pluripotency-related genes involved in the core hESC regulatory circuitry, including OCT4, SOX2, and NANOG, as well as CRYPTO 1 and 3, LCK, and HESX1.
Positive_regulation (high) of Gene_expression (expression) of OCT4
1) Confidence 0.31 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565131 Disease Relevance 0.18 Pain Relevance 0
GBs frequently overexpress genes typical of neural stem cells including Sox2 [106], Myc [27] and Oct4 [107].
Positive_regulation (overexpress) of Gene_expression (overexpress) of Oct4 in stem cells
2) Confidence 0.14 Published 2011 Journal Journal of Oncology Section Body Doc Link PMC3010739 Disease Relevance 1.09 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox