INT248921

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.48
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T cells 3
Klrd1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 33 58.00 Quite High
tolerance 6 50.64 Quite High
anesthesia 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunization 21 91.64 High High
Hypersensitivity 15 80.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By binding to different NKG2 subsets, CD94 could regulate the cytotoxicity and survival of NK cells and CD8+T cells upon reaction with their ligand [12-15].
CD94 Binding (binding) of in T cells
1) Confidence 0.26 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0.27 Pain Relevance 0.03
The results showed that only CD8+CD94+T cells from ACAID mice profoundly inhibited the proliferation of responder cells, CD8+CD94-T cells from ACAID mice as well as immunized mice showed no suppressive activity.
CD94 Binding (immunized) of in T cells
2) Confidence 0.24 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0.09 Pain Relevance 0
Although CD94 could pair with different NKG2 molecules, most CD94/NKG2 receptors on both NK and CD8+T cells have been shown to be CD94-NKG2A heterodimer in mice [8,11].
CD94 Binding (pair) of in T cells
3) Confidence 0.24 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0.12 Pain Relevance 0.03

General Comments

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