INT248928

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 0.42
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T cells 6
Anterior 1
Klrd1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 77 96.96 Very High Very High Very High
tolerance 14 93.12 High High
anesthesia 7 5.00 Very Low Very Low Very Low
isoflurane 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunization 49 99.32 Very High Very High Very High
Hypersensitivity 35 74.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The suppressive effect of CD8+CD94+T and CD8+CD94-T cells from ACAID mice on the proliferation of splenic MNC from naive mice (at 1:1 ratio) upon anti-CD3 mAb(1 ?
Positive_regulation (effect) of CD94 in T cells
1) Confidence 0.36 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0 Pain Relevance 0.04
However, it appears that CD94 is not a specific marker for CD8+Treg, as this molecule can be upregulated following T cell activation and CD8+CD94+T cells from immunized mice did not show suppression.
Positive_regulation (upregulated) of CD94 in T cells
2) Confidence 0.34 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0 Pain Relevance 0.07
Upregulation of the CD94-NKG2A receptor on splenic CD8+T cells of ACAID mice
Positive_regulation (Upregulation) of CD94 in T cells
3) Confidence 0.34 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0.07 Pain Relevance 0
Upregulation of CD94 on CD8+T Cells in Anterior Chamber-Associated Immune Deviation

Background

Positive_regulation (Upregulation) of CD94 in Anterior
4) Confidence 0.34 Published 2008 Journal BMC Immunol Section Title Doc Link PMC2566975 Disease Relevance 0 Pain Relevance 0.05
They found that CD94-NKG2A could be induced on CD8+T cells following TCR-mediated activation in vivo.
Positive_regulation (induced) of CD94 in T cells
5) Confidence 0.34 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0.18 Pain Relevance 0.09
The suppressive effect of CD8+CD94+T and CD8+CD94-T cells from ACAID mice on the proliferation of splenic MNC from naive mice (at 1:1 ratio) upon anti-CD3 mAb(1 ?
Positive_regulation (effect) of CD94 in T cells
6) Confidence 0.32 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0 Pain Relevance 0.04
The results showed that a significantly higher expression of CD94-NKG2A heterodimer on CD8+T cells was induced following OVA inoculation into the anterior chamber, and that AC-injection of antigen and immunization have a synergistic effect on the increase of CD8+CD94+T cells.
Positive_regulation (increase) of CD94 in T cells associated with immunization
7) Confidence 0.29 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0.17 Pain Relevance 0.09

General Comments

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