INT248934

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Context Info
Confidence 0.50
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.44
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T cells 4
anterior chamber 2
Klrd1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 44 95.40 Very High Very High Very High
tolerance 8 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunization 28 99.86 Very High Very High Very High
Hypersensitivity 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that the induced expression of CD94 molecule is associated with the inhibitory effect of CD8+T cells following OVA inoculation into the anterior chamber.
Positive_regulation (induced) of Gene_expression (expression) of CD94 in anterior chamber
1) Confidence 0.50 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0 Pain Relevance 0.09
Interestingly, we also found an increased expression of CD94-NKG2A in mice following conventional immunization.
Positive_regulation (increased) of Gene_expression (expression) of CD94 associated with immunization
2) Confidence 0.36 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0.19 Pain Relevance 0.09
The results showed that a significantly higher expression of CD94-NKG2A heterodimer on CD8+T cells was induced following OVA inoculation into the anterior chamber, and that AC-injection of antigen and immunization have a synergistic effect on the increase of CD8+CD94+T cells.
Positive_regulation (induced) of Gene_expression (expression) of CD94 in T cells associated with immunization
3) Confidence 0.36 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0.16 Pain Relevance 0.08
As both intracameral inoculation and conventional immunization could upregulate CD94-NKG2A expression, we examined the inhibitory effect of CD8+CD94+T cells from ACAID mice and immunized mice on the proliferation of splenic MNC in vitro.
Positive_regulation (upregulate) of Gene_expression (expression) of CD94 in T cells associated with immunization
4) Confidence 0.34 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2566975 Disease Relevance 0.10 Pain Relevance 0

General Comments

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