INT248968

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.20
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.09
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Csn2) extracellular region (Csn2)
Csn2 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate receptor 3 98.20 Very High Very High Very High
gABA 129 97.36 Very High Very High Very High
GABA receptor 9 92.32 High High
Action potential 16 76.44 Quite High
Neurotransmitter 30 74.48 Quite High
GABAergic 13 66.08 Quite High
Dopamine 75 50.00 Quite Low
antagonist 28 5.00 Very Low Very Low Very Low
agonist 28 5.00 Very Low Very Low Very Low
Glutamate 17 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 14 91.28 High High
Channelopathies 17 50.00 Quite Low
Night Blindness 9 39.56 Quite Low
Ocular Toxicity (including Many Sub-types) 1 37.96 Quite Low
Myopia 2 37.52 Quite Low
Deafness 1 6.24 Low Low
Hypokalemic Periodic Paralysis 29 5.00 Very Low Very Low Very Low
Ganglion Cysts 26 5.00 Very Low Very Low Very Low
Dystonia 10 5.00 Very Low Very Low Very Low
Malignant Hyperthermia 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Identification of the genetic defect responsible for CSNB2 led to the discovery of a novel Ca2+ channel ?
Regulation (responsible) of CSNB2
1) Confidence 0.20 Published 2010 Journal Pflugers Arch Section Body Doc Link PMC2883925 Disease Relevance 0.09 Pain Relevance 0.14
Alternatively, casein kinases are regulated by protein phosphatases and by metabotropic glutamate receptors [90,91], and perhaps persistent GABA stimulation alters these pathways.
Regulation (regulated) of casein associated with gaba and glutamate receptor
2) Confidence 0.01 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2567003 Disease Relevance 0 Pain Relevance 0.54

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox