INT249000

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Helt, Per2) cell differentiation (Helt) signal transduction (Per2)
protein binding transcription factor activity (Per2) DNA binding (Helt) cytoplasm (Per2)
Helt (Mus musculus)
Per2 (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 13 100.00 Very High Very High Very High
gABA 129 98.04 Very High Very High Very High
antagonist 28 68.76 Quite High
GABA receptor 9 57.20 Quite High
addiction 3 52.12 Quite High
Dopamine 75 50.00 Quite Low
agonist 28 5.00 Very Low Very Low Very Low
Neurotransmitter 23 5.00 Very Low Very Low Very Low
Glutamate 13 5.00 Very Low Very Low Very Low
Action potential 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 26 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Myopia 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Refractive Errors 1 5.00 Very Low Very Low Very Low
Retina Disease 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Ocular Hypertension 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To further test whether GABAergic suppression of PER2::LUC luminescence rhythms results from an effect on the core function of the retinal clock, we tested whether prolonged application of GABA can halt the molecular oscillation of the retinal clock.
GABAergic Spec (whether) Negative_regulation (suppression) of PER2 associated with gaba and gabaergic
1) Confidence 0.01 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2567003 Disease Relevance 0 Pain Relevance 0.48

General Comments

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