INT249121

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mtor) mitochondrion (Mtor) Golgi apparatus (Mtor)
endoplasmic reticulum (Mtor) nucleus (Mtor) kinase activity (Mtor)
Anatomy Link Frequency
synapses 2
Mtor (Rattus norvegicus)
Pain Link Frequency Relevance Heat
long-term potentiation 6 97.40 Very High Very High Very High
dopamine receptor 20 66.44 Quite High
agonist 24 44.64 Quite Low
Dopamine 26 44.32 Quite Low
Glutamate receptor 3 12.32 Low Low
Glutamate 1 9.20 Low Low
antagonist 11 5.00 Very Low Very Low Very Low
midbrain 3 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
Pyramidal cell 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 10 18.32 Low Low
Depression 3 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In hippocampal neurons, for example, an interaction of ERK and mTOR in increasing the translational capacity has recently been demonstrated after LTP-inducing stimulation and activation of neuromodulatory transmitter receptors (Gelinas et al. 2007; Tsokas et al. 2007), and a dopaminergic stimulation of rapamycin-sensitive local protein synthesis has been implicated in the activation of previously silent synapses (Smith et al. 2005).
Positive_regulation (increasing) of mTOR Binding (interaction) of in synapses associated with long-term potentiation
1) Confidence 0.20 Published 2008 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2567422 Disease Relevance 0 Pain Relevance 0.08

General Comments

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