INT249140

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Context Info
Confidence 0.67
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Was) protein complex assembly (Was) cytoplasm (Was)
Anatomy Link Frequency
row 1
T cells 1
Was (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Epstein-barr Virus 2 34.12 Quite Low
Wiskott-aldrich Syndrome 54 5.00 Very Low Very Low Very Low
Disease 28 5.00 Very Low Very Low Very Low
Immunodeficiency 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Eczema 4 5.00 Very Low Very Low Very Low
Thrombocytopenia 4 5.00 Very Low Very Low Very Low
Hemorrhage 4 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 4 5.00 Very Low Very Low Very Low
Uveitis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The WASP protein in patient T cells could have been transcribed primarily from a single allele if most somatic mutations persisted in cells and were only occasionally transcribed.
Transcription (transcribed) of WASP in T cells
1) Confidence 0.67 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2567846 Disease Relevance 0 Pain Relevance 0
On size analysis, RNA-derived fragments from T cells and NK cells of normal healthy individuals migrated as single peaks at the predicted 284 bp (Figure 5, top row, left and middle), and patient NK-cell fragments migrated as a single 283 bp peak, consistent with the germ line allele (Figure 5, row 2, left), indicating that transcribed WASP in these cell populations comes from a single source allele.
Transcription (transcribed) of WASP in row
2) Confidence 0.61 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2567846 Disease Relevance 0 Pain Relevance 0

General Comments

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